With 15 FA Cup fourth round ties to play, and with three League One sides still in the mix, it promises to be an exciting weekend of knockout football as teams battle it out for a place in the last 16 of the world's most famous cup competition.
For those looking for an upset, League One Bradford City face a daunting trip to Premier League leaders Chelsea whilst on Monday evening Rochdale host Stoke.
Elsewhere in-form West Ham will have to be wary of a potential banana skin. They must travel to League One high-flyers Bristol City who will fancy their chances against Sam Allardyce's side.
With pride, a financial boost and of course a place in history at stake, these lower league underdogs will be looking to emulate some of the teams who overcame the odds to produce the biggest FA Cup shocks of the last ten years.
Manchester City 1-2 Wigan Athletic, quarter-final 2014
With the previous season's FA Cup Final defeat to Wigan costing former manager Roberto Mancini his job, Manchester City boss Manuel Pellegrini knew his side must deliver against Championship outfit Wigan.
Although they were the current holders, the Latics were seen as huge underdogs as City paraded the Capital One Cup before kick-off.
But despite the presence of Sergio Aguero, Yaya Toure and David Silva, goals from Jordi Gomez and James Perch gave Uwe Rosler's side their second shock win over City in as many years.
Barnsley 1-0 Chelsea, quarter-final 2008
A Chelsea team that were the FA Cup holders and featuring John Terry, Michael Ballack and Nicolas Anelka amongst others was unceremoniously dumped out of the competition by Championship Barnsley.
The winner was scored by none other than ex Cheltenham Town striker Kayode Odejayi who met a cross from another former Robins' favourite - Martin Devaney – with a leaping header.
Manchester United 0-1 Leeds United, third round 2010
The Red Devils had never been knocked out of the third round or lost to lower league opposition under the reign of Sir Alex Ferguson, until rivals Leeds United stunned them at Old Trafford.
Few expected Leeds to get any sort of result, but a goal from striker Jermaine Beckford saw the League One side sailing into the fourth round draw.
Stevenage 3-1 Newcastle United, third round 2011
League Two Stevenage swept aside Premier League Newcastle despite there being 72 places between the two sides in the football ladder.
Stacy Long and Michael Bostwick gave Graham Westley's team a two goal lead before ten man Newcastle pulled a goal back through Joey Barton.
But there was still time for Boro to seal it with a third as Peter Winn slotted home in injury time to prompt wild celebrations and a pitch invasion from the home support.
Norwich City 0-1 Luton Town, fourth round 2013
Another Cheltenham Town link as current Robins' boss Paul Buckle masterminded the first win for a non-league team against a top division side for 24 years.
In one of the biggest FA Cup shocks in recent times, Buckle's Luton team outplayed their Premier League opponents and were full value for their win.
Substitute Scott Rendell was the hero, netting the winner ten minutes from time to silence the Canaries at Carrow Road.